The mode of assembly of alphavirus cores implies a mechanism for the disassembly of the cores in the early stages of infection

G Wengler - Archives of virology, 1987 - Springer
G Wengler
Archives of virology, 1987Springer
Conclusion Probably many different strategies will be used by viruses to disassemble viral
nucleoprotein complexes during the early stages of infection and the detailed model
described aboved may only apply to alphaviruses. On the other hand, the existence of a
cellular binding site which has to be saturated to a certain extent with the protein
components of viral nucleoproteins before viral nucleoprotein assembly can occur and
which binds the protein of the incoming viral nucleoprotein may be a feature which may also …
Conclusion
Probably many different strategies will be used by viruses to disassemble viral nucleoprotein complexes during the early stages of infection and the detailed model described aboved may only apply to alphaviruses. On the other hand, the existence of a cellular binding site which has to be saturated to a certain extent with the protein components of viral nucleoproteins before viral nucleoprotein assembly can occur and which binds the protein of the incoming viral nucleoprotein may be a feature which may also be used by other viruses.
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