A dysregulated balance of proinflammatory and anti-inflammatory host cytokine response early during therapy predicts persistence and mortality in Staphylococcus …

E Minejima, J Bensman, RC She, WJ Mack… - Critical care …, 2016 - journals.lww.com
Objectives: The contribution of individual immune response to Staphylococcus aureus
bacteremia on outcome has not been well studied. The objective was to relate the host
cytokine response to outcome of Staphylococcus aureus bacteremia. Design: Prospective
observational study. Setting: Three US university-affiliated medical centers. Patients: Adult
patients infected with Staphylococcus aureus bacteremia hospitalized between July 2012
and August 2014. Interventions: Blood specimens were obtained at Staphylococcus aureus …