N-terminal 10-and 12-kDa POMC fragments stimulate differentiation of lactotrophs

A Van Bael, VV Vijver, B Devreese, J Van Beeumen… - Peptides, 1996 - Elsevier
VAN BAEL, A., V. VANDE VIJVER, B. DEVREESE, J. VAN BEEUMEN AND C. DENEF. N-
terminal 10-and 12-kDa POMC fragments stimulate differentiation of lactotrophs. PEPTIDES
17 (7) 1219–1228, 1996.—Medium conditioned by a highly enriched population of
gonadotrophs, cultured as reaggregates in the presence of 0.01 nM GnRH, was
concentrated, separated on a reversed-phase HPLC column, and tested for activity on
lactotroph development in pituitary reaggregate cell cultures of 14-day-old rats. The number …