In vivo platelet activation in critically ill patients with primary 2009 influenza A (H1N1)
MT Rondina, BA Brewster, CK Grissom… - Chest, 2012 - Elsevier
Background Changes in platelet reactivity during 2009 influenza A (H1N1)(A [H1N1]) have
not been characterized. Methods We prospectively examined platelet activation and
cytokine responses in patients with A (H1N1)(n= 20), matched patients with bacterial
pneumonia (n= 15), and nonhospitalized, healthy control subjects (n= 10). Results Platelet-
monocyte aggregation was higher in patients with A (H1N1)(21.4%±4.7%) compared with
patients with pneumonia (10.9%±3.7%) and control subjects (8.1%±4.5%, P<. 05). Similarly …
not been characterized. Methods We prospectively examined platelet activation and
cytokine responses in patients with A (H1N1)(n= 20), matched patients with bacterial
pneumonia (n= 15), and nonhospitalized, healthy control subjects (n= 10). Results Platelet-
monocyte aggregation was higher in patients with A (H1N1)(21.4%±4.7%) compared with
patients with pneumonia (10.9%±3.7%) and control subjects (8.1%±4.5%, P<. 05). Similarly …
