Despite significant evidence implicating an important role for neutrophils in thrombosis, their
impact on the thrombotic process has remained a matter of controversy. Until 2010, platelets,
coagulation factors, fibrinogen and monocytes were implicated in the thrombotic process.
Several studies conducted over the last decade now support the growing notion that
neutrophils indeed do contribute significantly to this process. Neutrophils can contribute to
pathologic venous and arterial thrombosis or 'immunothrombosis' by the release of …