S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells
T Tsuneyoshi, K Kunimura, N Morihara - Nitric Oxide, 2019 - Elsevier
Garlic has been demonstrated to exert protective effects against oxidative damage using
numerous experimental models. The antioxidant effects of garlic are associated with the
activation of Nrf2-dependent gene expression. S-1-Propenylcysteine (S1PC) and S-
allylcysteine (SAC) are two predominant sulfur amino acids present in aged garlic extract;
however, the exact roles of these amino acids within the Keap1/Nrf2 system remain
unknown. We hypothesized that sulfur-containing amino acids derived from garlic could …
numerous experimental models. The antioxidant effects of garlic are associated with the
activation of Nrf2-dependent gene expression. S-1-Propenylcysteine (S1PC) and S-
allylcysteine (SAC) are two predominant sulfur amino acids present in aged garlic extract;
however, the exact roles of these amino acids within the Keap1/Nrf2 system remain
unknown. We hypothesized that sulfur-containing amino acids derived from garlic could …
