Gonadotroph cell adenomas of the pituitary gland occur more frequently than suspected and
account for as many as 24 per cent of macroadenomas in men. They generally are
recognized in middle-aged men who have a normal fertility history and present with the
visual abnormalities of a massive pituitary adenoma. The patients are characterized
hormonally by increased serum concentrations of intact FSH, accompanied often by
increased a and FSHß subunits, occasionally by increased LHß, and uncommonly by intact …