Ataxia-telangiectasia (AT) is perceived differently by neurologists, radiotherapists,
radiobiologists, cytogeneticists, immunologists, geneticists, and tumor biologists. The
neurologist sees a progressive cerebellar ataxia with onset in early childhood. The
radiotherapist worries about inadvertently treating patients with AT (that is, homozygotes)
with conventional, but for them contraindicated, doses of radiation. The radiobiologist sees a
public health problem involving 1% to 3% of the general population who as AT carriers …