In vivo effects of LPS on B lymphocyte subpopulationsmigration of marginal zone-lymphocytes and IgD-blast formation in the mouse spleen
PHP Groeneveld, T Erich, G Kraal - Immunobiology, 1985 - Elsevier
The aim of the present study was to analyze the effect of LPS on the localization and
differentiation of splenic B lymphocytesTherefore, we used a double immunoperoxidase
technique which enabled us to detect both the IgM+ IgD-marginal zone lymphocytes and the
IgM+ IgD+ follicular lymphocytes in the same tissue section. Next to a dramatic
disappearance of the predominantly IgM+ IgD-lymphocytes in the marginal zone shortly after
an intravenous injection of LPS, an increased number of these cells could be found in the …
differentiation of splenic B lymphocytesTherefore, we used a double immunoperoxidase
technique which enabled us to detect both the IgM+ IgD-marginal zone lymphocytes and the
IgM+ IgD+ follicular lymphocytes in the same tissue section. Next to a dramatic
disappearance of the predominantly IgM+ IgD-lymphocytes in the marginal zone shortly after
an intravenous injection of LPS, an increased number of these cells could be found in the …
