Recycling of docosahexaenoic acid in rat retinas during n-3 fatty acid deficiency.
AM Stinson, RD Wiegand, RE Anderson - Journal of lipid research, 1991 - ASBMB
About 50% of the fatty acids in retinal rod outer segments is docosahexaenoic acid [22: 6 (n-
3)], a member of the linolenic acid [18: 3 (n-3)] family of essential fatty acids. Dietary
deprivation of n-3 fatty acids leads to only modest changes in 22: 6 (n-3) levels in the retina.
We investigated the mechanism (s) by which the retina conserves 22: 6 (n-3) during n-3 fatty
acid deficiency. Weanling rats were fed diets containing 10%(wt/wt) hydrogenated coconut
oil (no n-3 or n-6 fatty acids), linseed oil (high n-3, low n-6), or safflower oil (high n-6, less …
3)], a member of the linolenic acid [18: 3 (n-3)] family of essential fatty acids. Dietary
deprivation of n-3 fatty acids leads to only modest changes in 22: 6 (n-3) levels in the retina.
We investigated the mechanism (s) by which the retina conserves 22: 6 (n-3) during n-3 fatty
acid deficiency. Weanling rats were fed diets containing 10%(wt/wt) hydrogenated coconut
oil (no n-3 or n-6 fatty acids), linseed oil (high n-3, low n-6), or safflower oil (high n-6, less …