[HTML][HTML] Dimorphic expression of cerebrosides in the mycopathogen Sporothrix schenckii
Major neutral glycosphingolipid components were extracted from Sporothrix schenckii, a
dimorphic fungus exhibiting a hyphal saprophytic phase and a yeast parasitic phase
responsible for chronic mycotic infections in mammalian hosts. These components, one from
the mycelial form and two from the yeast form, were purified and their structures were
elucidated by 1 H nuclear magnetic resonance (NMR) spectroscopy, electrospray ionization
mass spectrometry (ESI-MS), and tandem ESI-MS/MS. All three were characterized as …
dimorphic fungus exhibiting a hyphal saprophytic phase and a yeast parasitic phase
responsible for chronic mycotic infections in mammalian hosts. These components, one from
the mycelial form and two from the yeast form, were purified and their structures were
elucidated by 1 H nuclear magnetic resonance (NMR) spectroscopy, electrospray ionization
mass spectrometry (ESI-MS), and tandem ESI-MS/MS. All three were characterized as …