Cysteine Proteinase Inhibitors Kill Cultured Bloodstream Forms ofTrypanosoma brucei brucei

L Troeberg, RE Morty, RN Pike… - Experimental …, 1999 - Elsevier
Troeberg, L., Morty, RE, Pike, RN, Lonsdale-Eccles, JD, Palmer, JT, McKerrow, JH, and
Coetzer, THT 1999. Cysteine proteinase inhibitors kill cultured bloodstream forms
ofTrypanosoma brucei brucei. Experimental Parasitology91, 349–355. Trypanosoma brucei
bruceiis a causative agent of bovine trypanosomiasis (nagana), a disease of considerable
economic significance in much of Africa. Here we report investigations on the effects of
various irreversible cysteine proteinase inhibitors, including vinyl sulfones (VS), peptidyl …