Trypanosoma brucei: Killing of Bloodstream Formsin Vitroandin Vivoby the Cysteine Proteinase Inhibitor Z-Phe-Ala-CHN2
S Scory, CR Caffrey, YD Stierhof, A Ruppel… - Experimental …, 1999 - Elsevier
Scory, S., Caffrey, CR, Stierhof, Y.-D., Ruppel, A., and Steverding, D. 1999. Trypanosoma
brucei: Killing of bloodstream formsin vitroandin vivoby the cysteine proteinase inhibitor Z-
Phe-Ala-CHN2. Experimental Parasitology91, 327–333. Cysteine proteinases were tested
for their suitability as targets for chemotherapy of sleeping sickness using the peptidyl
inhibitor Z-Phe-Ala-diazomethyl ketone (Z-Phe-Ala-CHN2). In vitro, the inhibitory
concentration of Z-Phe-Ala-CHN; 2required to reduce the growth rate by 50% was 400 times …
brucei: Killing of bloodstream formsin vitroandin vivoby the cysteine proteinase inhibitor Z-
Phe-Ala-CHN2. Experimental Parasitology91, 327–333. Cysteine proteinases were tested
for their suitability as targets for chemotherapy of sleeping sickness using the peptidyl
inhibitor Z-Phe-Ala-diazomethyl ketone (Z-Phe-Ala-CHN2). In vitro, the inhibitory
concentration of Z-Phe-Ala-CHN; 2required to reduce the growth rate by 50% was 400 times …
