Whole-body glucose utilization during euglycemic-hyperinsulinemic clamp. The left panel represents the insulin-stimulated systemic glucose uptake (M) per kg FFM during clamp in both patient groups. The middle and right panels depict the correlation between whole-body glucose utilization and the rate constants k3 (middle) and K (right) for F-18-FDG uptake from three-compartment modeling. K is a PET parameter of F-18-FDG clearance from blood to muscle.